35 results
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
vasculitis • Hematologic ... criteria for 1) hematologic ... (12%) • giant cell ... hematopoietic stem cells ... cells NEJM Review
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Differential Diagnosis Algorithm ... Acute • Myloid ... CD3 Chronic • Myloid ... Blood #Disorders #hematology ... Differential #Diagnosis #Algorithm
Sickle cell anemia and Howell Jolly bodies (nuclear remnants).

 - Dr. Abubaker Elshaikh
@ElshaikhMD

#SickleCell #HowellJolly #Body #Bodies
Sickle cell anemia ... #HowellJolly #Body ... #Bodies #Pathology ... #Hematology #Smear
Primary Bone Tumors - Differential Diagnosis Algorithm 

Metastatic - Most common tumour in adults
 - Breast
Differential Diagnosis Algorithm ... Non-Malignant • Giant Cell ... tumours • Multiple Myeloma ... Differential #Diagnosis #Algorithm ... Causes #Oncology #Radiology
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Plasma cell leukemia ... other forms of myeloma ... primary plasma cell ... Clinical #Smear #Hematology ... #Pathology
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Multiple Myeloma ... osteolytic lesions and pathologic ... marrow plasma cells ... plasma clonal cell ... #Multiple #Myeloma
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or on bone ... CML (Chronic Myeloid ... • Neutrophils (myeloid ... AML (Acute Myeloid ... #Leukemia #Hematology
Vertebral Body Abnormalities

A sheet of common (and uncommon) vertebral body findings, because a completely “normal” spine
uncommon) vertebral body ... Disease Sickle Cell ... Sclerotic Mets Bone ... Abnormalities #Radiology ... #MSK #Pathology
Bone Lesion on X-Ray - Differential Diagnosis Algorithm 
Exostotic
 • Osteochondroma
Asymptomatic &/or Non-Active Bone Scam
 •
Bone Lesion on X-Ray ... Differential Diagnosis Algorithm ... Lesions • Multiple Myeloma ... malignant) • Giant Cell ... Differential #Diagnosis #Algorithm
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic Algorithm ... Increased red cell ... hyperplasia of bone ... Increased red cell ... Causes #Workup #Hematology