19 results
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Somatic) Syndrome Clinical ... Syndrome: • Common Clinical ... criteria for 1) hematologic ... cells NEJM Review ... Autoinflammatory #Somatic #rheumatology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Significance (MGUS ... - Differential Diagnosis ... #Differential #Diagnosis ... #hematology #oncology
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
, low-risk MGUS ... whom there are no clinical ... concerning for myeloma ... Biopsy #algorithm #diagnosis ... #management #hematology
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Plasma cell leukemia ... other forms of myeloma ... rouleaux #formation #Clinical ... #Smear #Hematology ... #Pathology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... marrow plasma cells ... to the plasma cell ... #Significance #hematology ... #diagnosis #oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Lymphoma (HCV) • CLL ... POEMS (Sclerotic myeloma ... POEMS (Sclerotic myeloma ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... and laboratory diagnosis ... non-specific red cell ... hemolytic #anemia #Hematology ... #Pathology #Smear
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Multiple Myeloma ... marrow plasma cell ... • CML, B and T cell ... #Gammopathies #MGUS ... #diagnosis #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... significance (MGUS ... ), CLL, Myeloma ... hemolytic #anemia #hematology ... #diagnosis
Myeloma: In this BM core, most plasma cells contain cytoplasmic immunoglobulin (Russell bodies).

They're difficult to identify
Myeloma: In this ... core, most plasma cells ... #Myeloma #CD138 ... PlasmaCells #BoneMarrow #Clinical ... #Pathology #Hematology