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VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
alveolitis, ear and ... thromboembolic disease ... Abnormalities: macrocytic anemia ... cells NEJM Review ... Autoinflammatory #Somatic #rheumatology
Diagnosis of active multiple myeloma is not just CRAB; it's actually "SLiM CRAB" @Majorajay & @Vincentrk #MultipleMyeloma
Diagnosis of active ... multiple myeloma ... CRAB #SLIMCRAB #Oncology ... #HemeOnc #Hematology ... Hypercalcemia #Anemia
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia Fanconi Anemia Acquired Aplastic Anemia Dyskeratosis Congenita & Telemore Biology
and Bone Marrow ... Failure Syndromes ... Shwachman-Diamond Syndrome ... #Pancytopenia #Syndromes ... #diagnosis #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Summary myelo ( ... cytopenias (usually anemia ... Management #treatment #hematology ... #oncology
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases Acanthocyte (spur cell), Basophilic stippling, Bite cell,
Pathologic Red Blood ... ) Morphologies and ... Associated Diseases ... #Hematology #Diagnosis ... Basis of Disease
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Iron deficiency anemia ... lymphoma, Multiple myeloma ... lymphoma, Multiple myeloma ... #differential #diagnosis ... #hematology #microscopy
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Multiple Myeloma ... 40 ml/min A - Anemia ... plasmacytoma, POEMs syndrome ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Multiple Myeloma ... Diagnosis and Management ... demineralization) • Renal disease ... pathologic fx) ... #oncology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Formation • Multiple Myeloma ... Myelodysplastic Syndromes ... • Rule out B12 and ... Algorithm #Causes #Hematology
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Diagnostic Algorithm ... chronic kidney disease ... - Vitamin B12 and ... Underproduction #Algorithm #hematology ... #diagnosis #differential
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