121 results
diagnosis differential rheumatology management dermatology symptoms hepatology neurology oncology algorithm causes microscopy physicalexam treatment photo workup manifestations monoclonal pathophysiology radiology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... : • Common Clinical ... thromboembolic disease ... vasculitis • Hematologic ... cells NEJM Review
Hypersegmented neutrophil in a case of acute myeloid leukemia. Dysplastic neutrophils are typically hypolobated but can be
case of acute myeloid ... neutrophils #AML #Clinical ... #Hematology #Pathology
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Aggressive disease ... other forms of myeloma ... rouleaux #formation #Clinical ... #Smear #Hematology ... #Pathology
Parinaud's Syndrome What? - Impaired upgaze - Light-near dissociation - Convergence retraction nystagmus - Eyelid retraction (Collier's
Parinaud's Syndrome ... retraction nystagmus - Eyelid ... retraction (Collier's sign ... → "setting sun sign ... " - Vascular disease
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
myelodysplastic syndrome ... • Myeloid hemopathy ... appearing during the disease ... differential #diagnosis #dermatology ... #oncology #clinical
A non-subtle example of true Sezary syndrome. Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear ... #Microscopy #Hematology
Castleman's Disease and Associated Syndromes HYALINE VASCULAR VARIANT • unicentric, HHV8-ve, children and young. • Hyalinized vessels
Castleman's Disease ... and Associated Syndromes ... Pathogenesis "IL6 syndrome ... cell disorders (myeloma ... Variants #Diagnosis #Pathology
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Multiple Myeloma ... Management Summary Clinical ... Signs: • hyperCalcemia ... demineralization) • Renal disease ... osteolytic lesions and pathologic
Rheumatoid Arthritis Summary MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Tunnel, Sicca Syndrome ... Scleritis, Heart Disease ... Nodules, Pulmonary Disease ... RA #diagnosis #rheumatology ... #signs #symptoms
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Alzheimer’s Disease ... Pathogenesis and Clinical ... mutations - Down syndrome ... chromosome 21) Signs ... geriatrics #diagnosis #signs
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