7824 results
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
DNA, RNA, and myelin ... The classic clinical ... #Pathophysiology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
directed towards the myelin ... transplantation CLINICAL ... the underlying pathophysiology ... specific therapy, the clinician
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... activation -> diffuse myelin ... Clinical Presentation ... : The clinical
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Somatic) Syndrome Clinical ... Syndrome: • Common Clinical ... thrombocytopenia, multiple myeloma ... conditions - multiple myeloma ... peripheral blood myeloid
Priapism 

Secondary Causes:
Medications- intracavernosal injections, anticoagulants, PDE5 inhibitors, alpha blockers, methylphenidate, cocaine
Any hyperviscosity syndrome (SCD, leukemia,
SCD, leukemia, myeloma ... or are zebras (…amyloid
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Pathogenesis and Clinical ... of cases): - Amyloid ... Down syndrome (amyloid ... AlzheimersDisease #Dementia #pathophysiology
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
case of acute myeloid ... neutrophils #AML #Clinical
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
POEMS syndrome, myeloma ... , secondary amyloid
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Clinical suspicion ... Amyloidosis Clinical ... Bone/Joint: • Amyloid ... (AMYLOID ANGIOPATHY ... weight loss • Eyelid
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... the different pathophysiologic ... #Diabetes #Pathophysiology