624 results
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
• Acute stroke syndromes ... Paraneoplastic syndrome ... Inflammatory: Myeloma ... Lack of UMN/LMN signs ... Differential #Diagnosis #neurology
Parinaud's Syndrome
What?
 - Impaired upgaze
 - Light-near dissociation
 - Convergence retraction nystagmus
 - Eyelid retraction (Collier's
Parinaud's Syndrome ... retraction nystagmus - Eyelid ... retraction (Collier's sign ... → "setting sun sign ... diagnosis #pineal #neurology
Priapism 

Secondary Causes:
Medications- intracavernosal injections, anticoagulants, PDE5 inhibitors, alpha blockers, methylphenidate, cocaine
Any hyperviscosity syndrome (SCD, leukemia,
hyperviscosity syndrome ... SCD, leukemia, myeloma ... or are zebras (…amyloid ... Diagnosis #Management #Urology
Parinaud's syndrome
What?
 • Light-near dissociation (tectal pupils)
 • Convergence retraction nystagmus
 • Eyelid retraction (Collier's sign)
Parinaud's syndrome ... retraction nystagmus • Eyelid ... retraction (Collier's sign ... "setting sun" sign ... #neurology #diagnosis
Central Cord Syndromes
 - Anterior Cord Syndrome
 - Central Cord Syndrome
 - Brown Sequard Syndrome

#CentralCord #Syndromes
Central Cord Syndromes ... Anterior Cord Syndrome ... - Central Cord Syndrome ... Brown Sequard Syndrome ... #BrownSequard #Neurology
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
Paraprotein-associated (POEMS syndrome ... , myeloma, secondary ... amyloid), Paraneoplastic ... diagnosis #causes #neurology
Guillain-Barre Syndrome
An acute polyneuropathy (disorder Of the peripheral nervous System).
Symptoms are Often symmetrical and progress Over
Guillain-Barre Syndrome ... GuillainBarre #Syndrome ... #Diagnosis #Neurology ... #Signs
Thyroid Eye Signs 
Lid Signs
    Dalrymple’s Sign: Lid Retraction.
    Von
Thyroid Eye Signs ... Lid Signs ... Dalrymple’s Sign ... lag of the upper eyelid ... Vigoroux Sign: Eyelid
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
clinical context and signs ... , HIV serology, ... Abdominal compartment syndrome ... myoglobin • Myeloma ... • Cardio-renal syndrome
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... thrombocytopenia, multiple myeloma ... myelodysplastic syndrome ... conditions - multiple myeloma ... peripheral blood myeloid