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symptoms signs differential management neurology algorithm causes syndrome infectiousdiseases treatment lifecycle cdc endocrinology parasite msk cardiology psychiatry rheumatology complications clinical
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... the spinal cord (Myelopathy ... Weakness: - Weakness ... bouts of HTN Diagnostic ... Transverse Myelitis Diagnosis
Neurological Patterns of Weakness • Hemispheric lesion • Brainstem lesion • Spinal cord lesion • Polyneuropathy
Neurological Patterns of Weakness ... Polyneuropathy • Myopathy ... Neurology #Patterns #Weakness ... #diagnosis #distribution
Myositis and Myopathies #ESR #CK #Differential diagnosis of myopathy #Inflammatory #myopathies #Dermatomyositis #muscle weakness #Polymyositis #Inclusion body myositis #Polymyalgia rheumatica #Fibromyalgia #Hypothyroid myopathy #Muscle stiffness #Drug-induced
#Differential diagnosis ... of myopathy # ... Dermatomyositis #muscle weakness ... #Hypothyroid myopathy ... Statin-induced myopathy
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
symmetric muscle weakness ... symmetric muscle weakness ... Fever, No muscle weakness ... Proximal muscle weakness ... #differential #diagnosis
Myelopathy - Injury to the entire spinal cord - Signs and Symptoms • Ataxia (early sign)
Myelopathy - Injury ... • Gross motor weakness ... early signs) #Myelopathy ... #diagnosis #signs
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
80%) - Proximal Weakness ... 10%) - Proximal Weakness ... femoral heads • Myopathy ... Complications #pathophysiology ... signs #symptoms #diagnosis
Causes of Peripheral Weakness - With and Without Sensory Changes - Differential Diagnosis Algorithm With Sensory Changes:
of Peripheral Weakness ... - Differential Diagnosis ... • No Objective Weakness ... Oculomotor • Myopathy ... #Differential #Diagnosis
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Elevation (Pain > Weakness ... Critical Illness Myopathy ... Chronic Causes (Weakness ... PROXIMAL MUSCLE WEAKNESS ... #differential #diagnosis
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy • Central or peripheral neurologic disease
Proximal Muscle Weakness ... Mimic Inflammatory Myopathy ... Mitochondrial myopathy ... MuscleWeakness #Myopathy ... #mimics #diagnosis
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... level of muscle weakness ... /full triad at diagnosis ... have significant weakness ... Autoimmune #Myositis #diagnosis
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