128 results
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... proximal myalgia and weakness ... symmetric muscle weakness ... IU/I • SAMS clinical ... (SAMS-CI) • EMG
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy
 • Central or peripheral neurologic disease
Causes of Proximal ... Muscle Weakness ... Mimic Inflammatory Myopathy ... Mitochondrial myopathy ... MuscleWeakness #Myopathy
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
Creatine Kinase - Causes ... immobility • Critical ... Illness Myopathy ... - Inflammatory myopathy ... polymyositis, necrotizing myopathy
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Weakness • Spinal ... Guillain-Barre syndrome ... heavy metals), Critical ... Mitochondrial myopathy
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Causes of Peripheral ... Weakness without ... Lambert-Eaton Myasthenic Syndrome ... • Congenital Myopathy ... Diagnosis #Algorithm #Causes
Causes of Peripheral Weakness - With and Without Sensory Changes - Differential Diagnosis Algorithm
With Sensory Changes:
Causes of Peripheral ... Weakness - With ... • No Objective Weakness ... Oculomotor • Myopathy ... Diagnosis #Algorithm #Causes
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... level of muscle weakness ... anti-synthetase syndrome ... and anti-HMGCR myopathy ... have significant weakness
Hypercalcemia - EKG Findings
Causes of Hypercalcemia 
• Malignancy 
• Milk-alkali syndrome 
• Vitamin D toxicity 
•
Hypercalcemia - EKG ... Findings Causes ... • Milk-alkali syndrome ... #Differential #Causes ... #Diagnosis #Cardiology
Brugada syndrome with non-sustained VT; sodium channel blocking drugs (e.g. amio, procainamide) can be dangerous here!

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Brugada syndrome ... blocking drugs (e.g ... amalmattu #Brugada #syndrome ... #EKG #Clinical ... #Cardiology #NSVT
Myoedema in Hypothyroidism on Physical Exam

Hypothyroidism is a clinical syndrome resulting from the production, secretion or
syndrome resulting ... and scaly skin, myopathy ... Myopathy due to ... characterized by muscle weakness ... reflex hammer, caused