128 results
Neurological Patterns of Weakness
 • Hemispheric lesion
 • Brainstem lesion
 • Spinal cord lesion
 • Polyneuropathy
Neurological Patterns of Weakness ... Polyneuropathy • Myopathy ... #Neurology #Patterns ... #Weakness #diagnosis
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy
 • Central or peripheral neurologic disease
Proximal Muscle Weakness ... Mimic Inflammatory Myopathy ... or peripheral neurologic ... Mitochondrial myopathy ... differential #causes #neurology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Guillain-Barre syndrome ... Lambert Eaton Syndrome ... Mitochondrial myopathy ... differential #diagnosis #neurology
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
Myalgia, Muscle weakness ... of movement, Deafness ... Carpal timel syndrome ... hypertrophy, Proximal myopathy ... Symptoms #Diagnosis #PhysicalExam
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
of Peripheral Weakness ... No Objective Weakness ... Lambert-Eaton Myasthenic Syndrome ... • Congenital Myopathy ... #Neurology #Differential
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
• Acute stroke syndromes ... Paraneoplastic syndrome ... Lambert-Eaton - Isaacs' syndrome ... Myopathy: ... Differential #Diagnosis #neurology
Causes of Peripheral Weakness - With and Without Sensory Changes - Differential Diagnosis Algorithm
With Sensory Changes:
of Peripheral Weakness ... • No Objective Weakness ... Oculomotor • Myopathy ... #Peripheral #Weakness ... #Sensory #Neurology
Myoedema in Hypothyroidism on Physical Exam

Hypothyroidism is a clinical syndrome resulting from the production, secretion or
is a clinical syndrome ... Myopathy due to ... characterized by muscle weakness ... Hypothyroidism #PhysicalExam ... clinical #video #neurology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... level of muscle weakness ... anti-synthetase syndrome ... and anti-HMGCR myopathy ... have significant weakness
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
proximal myalgia and weakness ... symmetric muscle weakness ... Guillain-Barré syndrome ... antisynthetase syndrome ... Lambert-Eaton myasthenic syndrome