11 results
diagnosis differential lupus management myopathy sle systemic vasculitis autoimmune classification myositis treatment cerebritis cns complications cryoglobulinemia cryoglobulins dermatology idiopathic iims
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... 80%) - Proximal Weakness ... 10%) - Proximal Weakness ... femoral heads • Myopathy ... Complications #pathophysiology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... Demyelinating Syndrome ... Aseptic Meningitis, Myelopathy ... Disease, PRES Pathophysiology ... CNS #neurology #rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... level of muscle weakness ... anti-synthetase syndrome ... have significant weakness ... Myositis #diagnosis #rheumatology
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
proximal myalgia and weakness ... symmetric muscle weakness ... Guillain-Barré syndrome ... systemic lupus erythematosus ... antisynthetase syndrome
NPSLE - Neurological and Psychiatric Manifestations of Systemic Lupus Erythematosus • Central: Aseptic meningitis, Cerebrovascular disease,
Systemic Lupus Erythematosus ... Demyelinating syndrome ... Seizure disorder, Myelopathy ... Guillain-Barre syndrome ... #SLE #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Hyperviscosity Syndrome ... purpura, Arthralgia, Weakness ... 20% Sjögren's syndrome ... systemic lupus erythematosus ... classification #rheumatology
Idiopathic Inflammatory Myopathies (IIM's) RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's) • Overlap Myositis
RASH + MUSCLE WEAKNESS ... Any inflammatory myopathy ... antisynthetase syndrome ... Severe proximal weakness ... IIMs #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
ischemia - Skin: erythematous ... myalgia and muscle weakness ... • Cogan Syndrome ... systemic lupus erythematosus ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
ischemia • Skin: Erythematous ... Myalgia and muscle weakness ... vasculitis • Behcet syndrome ... vasculitis • Cogan syndrome ... Differential #Diagnosis #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... Antisynthetase syndrome ... ANTI-SYNTHETASE SYNDROME ... paraneoplastic syndrome ... #rheumatology #
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