11 results
diagnosis management differential erythematosus systemic vasculitis classification treatment autoimmune cerebritis cns complications cryoglobulins hematology manifestations monoclonal msk muscle musculoskeletal myopathy
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... femoral heads • Myopathy ... Erythematosus #SLE ... Complications #pathophysiology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Demyelinating Syndrome ... Aseptic Meningitis, Myelopathy ... Disease, PRES Pathophysiology ... CNS #neurology #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
purpura, Arthralgia, Weakness ... diseases: - 10% SLE ... (e.g. systemic lupus ... erythematosus (SLE ... classification #rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
level of muscle weakness ... anti-synthetase syndrome ... Can also see mechanics ... have significant weakness ... Myositis #diagnosis #rheumatology
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
proximal myalgia and weakness ... symmetric muscle weakness ... Guillain-Barré syndrome ... GBS), systemic lupus ... erythematosus (SLE
NPSLE - Neurological and Psychiatric Manifestations of Systemic Lupus Erythematosus • Central: Aseptic meningitis, Cerebrovascular disease,
Demyelinating syndrome ... Seizure disorder, Myelopathy ... Guillain-Barre syndrome ... Erythematosus #SLE ... #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
late-onset nemaline myopathy ... Immunotactoid GN & Cryoglobulinemic ... WM: Vasculitis (Cryoglobulinemic ... to cold IgG • Lupus ... Paraproteinemias #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
ANCA +MPO) • Cryoglobulinemic ... myalgia and muscle weakness ... such as systemic lupus ... vasculitis, and SLE ... differential #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... overlaps with RA, SLE ... demyelinating disease, myelopathy ... Vasculitis: • 7%, Cryoglobulinemia ... #Rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Myalgia and muscle weakness ... / ANCA + MPO) Cryoglobulinemic ... vasculitis • Cogan syndrome ... Differential #Diagnosis #Rheumatology
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