16 results
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
Symptoms: Tiredness ... Myalgia, Muscle weakness ... Carpal timel syndrome ... hypertrophy, Proximal myopathy ... reflexes, Anaemia #Hypothyroid
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
proximal myalgia and weakness ... any time during treatment ... symmetric muscle weakness ... , hypothyroid-induced ... syndrome (GBS),
Myoedema in Hypothyroidism on Physical Exam

Hypothyroidism is a clinical syndrome resulting from the production, secretion or
is a clinical syndrome ... varied clinical symptoms ... characterized by muscle weakness ... clinical #video #neurology ... endocrinology #hypothyroid
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
level of muscle weakness ... less systemic symptoms ... anti-synthetase syndrome ... have significant weakness ... after 2 years of treatment
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
• Acute stroke syndromes ... Paraneoplastic syndrome ... Myopathy: ... Endocrinopathies: Hypothyroid ... Differential #Diagnosis #neurology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Demyelinating Disease (MS ... Guillain-Barre syndrome ... Mitochondrial myopathy ... differential #diagnosis #neurology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Upper extremity weakness ... anesthesia. leg weakness ... pathophysiology #signs #symptoms ... #msk #orthopedics ... #neurology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
findings: • Symptoms ... - Radiation myelopathy ... - Radiation myelopathy ... MCTD, Sjogren syndrome ... disorders #diagnosis #neurology
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... Lower motor neuron symptoms ... Upper motor neuron symptoms ... - Radiation myelopathy ... differential #diagnosis #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
variable degree of weakness ... Limb- proximal weakness ... immunologic assay - MuSK ... Severe bulbar weakness ... diagnosis #management #neurology