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Diffuse large B cell lymphoma (DLBCL) - Management and Treatment Algorithm

By Matthew Ho, MD PhD @MatthewHoMD

#Diffuse
Diffuse large B cell ... Management and Treatment ... Diffuse #large #Bcell ... DLBCL #Management #Treatment ... Algorithm #oncology #hematology
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathway Activation (C3a ... and C5a) -> Anaphylatoxins ... Cytokines, Mast Cells ... perivascular inflammatory cells ... Pathophysiology #Rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
lymphocytes/Mature B cell ... cells can infiltrate ... or basket cells ... microglobulin Treatment ... workup #oncology #hematology
Treatments for Sickle Cell disease

#Sicklecell #sicklecelldisease #sicklecellanemia, #sicklecells #sickle #hematology #anemia #clinical #pediatrics #FOAM #FOAMed
Treatments for Sickle ... Cell disease ... sicklecells #sickle #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... Allogeneic stem cell ... only curative treatment ... Diagnosis #Management #treatment ... #hematology #oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Reed-Sternberg (RS) Cells ... ~10% - B-Cell ... Responsive to Treatment ... growth, response to treatment ... pathophysiology #Hematology
Vasculitis Management - ACR/VF 2021 Guidelines for Treatment & Management
 • Giant Cell Arteritis (GCA)
 •
Guidelines for Treatment ... Management • Giant Cell ... Vasculitis #Management #Treatment ... Guidelines #algorithm #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
lymphocytes, smudge cells ... Transformation to large cell ... transformation) Treatment ... AIHA, PRCA) • Treatment ... Leukemia #oncology #hematology
Krabbe Disease 

Check out this interesting case of Krabbe disease, a rare genetic leukodystrophy. Diagnosis was
testing and expedite treatment ... failure, cerebellar ataxia ... (from globoid cell ... Cho Tx: Stem cell
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
- often breast CA ... , small cell lung ... CA, lymphoma, melanoma ... Diagnosis #causes #hepatology