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diagnosis differential causes algorithm hematology management rheumatology neurology pathophysiology treatment hepatology mnemonic endocrinology anemia clinical table hemolytic syndrome cardiology comparison
Cardiomyopathies Manifestations of cardiomyopathy (CM) range from microscopic alterations in cardiac myocytes to fulminant Heart Failure
alterations in cardiac myocytes ... selenium) • Autoimmune
CARDIAC MYOCYTE POTENTIALS #Pathophysiology #Cardiology #Cardiac #Myocyte #Ventricular #ActionPotentials #Channels #Phases
CARDIAC MYOCYTE ... Cardiology #Cardiac #Myocyte
Cardiac Myocyte Contractile cycle - Ca2+ binds to TnC → TnI is inhibited → conformational change
Cardiac Myocyte ... Pathophysiology #Cardiology #Myocyte
Action potential in cardiomyocytes The action potential in typical cardiomyocytes is composed of 5 phases (0-4), beginning
ActionPotential #Myocytes
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... NECROTIZING AUTOIMMUNE ... levels 50X ULN • Myocyte ... Diseases: • PBC, autoimmune ... antibodies #Autoimmune
Causes of Leukocytosis and Leukopenia - Differential Diagnosis • Eosinophilia (AEC > 500, hypereosinophilia > 1500):
Infection, Malignancy, Autimmune ... Lymphocytopenia: Infections, Autoimmune ... Infections, Drugs, Autoimmune ... Infection, Malignancy, Autoimmune
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm Autoimmune: • Isolated • Polyglandular autoimmune syndrome 1 •
Diagnosis Algorithm Autoimmune ... Polyglandular autoimmune ... Polyglandular autoimrnune
Hemolysis Classification - Intrinsic and Extrinsic Causes Commentary: Another way to think of immune hemolysis would be
hemolysis would be autoimmune ... already listed) and alloimmune
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolysis: • Autoimmune ... Anemias (AIHAs) • Alloimmune
Innate Immune Cells - Pathophysiology The innate immune system consists of granulocytes, mast cells, natural killer cells,
killer cells, and monocytes ... Monocytes and neutrophils ... Monocytes and B-cells
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