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diagnosis differential neurology clinical physicalexam video algorithm causes management signs symptoms rheumatology msk pathophysiology endocrinology sign orthopedics syndrome dermatology treatment
Myositis and Myopathies #ESR #CK #Differential diagnosis of myopathy #Inflammatory #myopathies #Dermatomyositis #muscle weakness #Polymyositis #Inclusion body myositis #Polymyalgia rheumatica #Fibromyalgia #Hypothyroid myopathy #Muscle stiffness #Drug-induced
Myositis and Myopathies ... #Inflammatory #myopathies ... #Dermatomyositis ... #muscle weakness ... #Hypothyroid myopathy
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
symmetric muscle weakness ... Anti-Jo, +Anti-Mi2 Dermatomyositis ... symmetric muscle weakness ... Fever, No muscle weakness ... Proximal muscle weakness
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Elevation (Pain > Weakness ... Critical Illness Myopathy ... Chronic Causes (Weakness ... PROXIMAL MUSCLE WEAKNESS ... : dermatomyositis
Dermatomyositis A middle-aged man describes progressive difficulty combing his hair and rising from a seated position over
Dermatomyositis ... This is a case of dermatomyositis ... proximal muscle weakness ... usually indicates myopathy ... AndreMansoor #Dermatomyositis
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... level of muscle weakness ... Dermatomyositis ... and anti-HMGCR myopathy ... have significant weakness
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm No Objective Weakness • Cardio-pulmonary disease
of Peripheral Weakness ... No Objective Weakness ... • Congenital Myopathy ... Statin Toxicity • Dermatomyositis ... #Peripheral #Weakness
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Myopathy: ... mediated necrotizing myopathy ... • Metabolic myopathies ... Muscle Biopsy: Dermatomyositis ... certain drug-induced myopathies
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
levels • EMG DERMATOMYOSITIS ... dermatomyositis ... cancer-associated adult dermatomyositis ... of the time) Dermatomyositis ... association with dermatomyositis
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
proximal myalgia and weakness ... symmetric muscle weakness ... • Inflammatory myopathy ... polymyositis, dermatomyositis ... Statin-induced myopathy
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Mitochondrial myopathy ... , Polymyositis/dermatomyositis ... Neuromuscular #Weakness
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