18 results
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
– symptoms and signs ... Carpal timel syndrome ... hypertrophy, Proximal myopathy ... #Symptoms #Diagnosis ... #PhysicalExam #Endocrinology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... heliotrope rash, Shaw sign ... , holster sign, ... anti-synthetase syndrome ... and anti-HMGCR myopathy
Diabetes Insipidus vs Syndrome of Inappropriate ADH (SIADH) - Comparison Table

Diabetes Insipidus - Inadequate ADH
SIADH -
Diabetes Insipidus vs Syndrome ... ) - Comparison Table ... Pathophysiology #Signs ... #Symptoms #Diagnosis ... #Endocrinology
Acute Coronary Syndrome - Diagnostic Likelihood Ratios for Symptoms and Physical Examination. 

Source:  Does This
Acute Coronary Syndrome ... - Diagnostic Likelihood ... #EBM #Diagnosis ... #Cardiology #ACS ... AcuteCoronarySyndrome #Symptoms #Signs
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Anti-Synthetase Syndrome ... Mediated Necrotizing Myopathy ... MSAs #clinical #diagnosis ... #rheumatology #table
Hyperthyroidism – symptoms and signs. 

Symptoms:

Weight loss, Increased appetite, Irritability/behaviour change, Restlessness, Malaise, Stiffness, Muscle weakness,
– symptoms and signs ... ), Sweating Signs ... loss, Proximal myopathy ... Hyperthyroidism #Symptoms #Signs ... #Diagnosis #Endocrinology
Cardiorenal Syndrome (CRS) Types
 • Type 1 - Acute CRS: Alteration of renal perfusion is the
Cardiorenal Syndrome ... Type 3 - Acute RCS ... Hypertension, CKD induced myopathy ... #Cardiorenal #Syndrome ... #CRS #Types #cardiology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Motor Nerves: ALS ... Guillain-Barre syndrome ... Lambert Eaton Syndrome ... Mitochondrial myopathy ... #differential #diagnosis
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
- Differential Diagnosis ... Lack of UMN/LMN signs ... proximal weakness Myopathy ... mediated necrotizing myopathy ... #Differential #Diagnosis
Clinical Effects of Large and Small Pituitary Tumours
Local complications - Headache, Visual field defect, Disconnection hyperprolactinaemia,
gain, Bruising, Myopathy ... Pituitary #Tumors #Signs ... #Symptoms #Diagnosis ... #Endocrinology