36 results
differential neurology management causes algorithm rheumatology treatment chestpain ebm myositis signs symptoms syndromes acutecoronarysyndrome angina atypical autoimmune cardiac cardiomyopathy classification
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... proximal myalgia and weakness ... symmetric muscle weakness ... IU/I • SAMS clinical ... #diagnosis #management
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
immobility • Critical ... Illness Myopathy ... - Inflammatory myopathy ... polymyositis, necrotizing myopathy ... #differential #diagnosis
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Motor Nerves: ALS ... heavy metals), Critical ... Mitochondrial myopathy ... #differential #diagnosis
Idiopathic Inflammatory Myopathies (IIM's) RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's) • Overlap Myositis
Any inflammatory myopathy ... antisynthetase syndrome ... Inflammatory myopathy ... #IIMs #diagnosis ... #dermatology #Myopathy
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... level of muscle weakness ... anti-synthetase syndrome ... /full triad at diagnosis ... and anti-HMGCR myopathy
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Diagnosis Framework ... • Acute stroke syndromes ... Myopathy: ... mediated necrotizing myopathy ... #Differential #Diagnosis
Generalized Weakness - Differential Diagnosis Framework "l feel weak": • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis •
Generalized Weakness ... - Differential Diagnosis ... I am weak": • Myopathy ... Rhabdomyolysis, Critical ... Polyneuropathy, ALS
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm No Objective Weakness • Cardio-pulmonary disease
of Peripheral Weakness ... - Differential Diagnosis ... Lambert-Eaton Myasthenic Syndrome ... • Congenital Myopathy ... #Differential #Diagnosis
Hypothyroidism – symptoms and signs. Symptoms: Tiredness/malaise, Weight gain, Anorexia, Cold intolerance, Poor memory, Change in appearance, Depression, Poor libido,
Myalgia, Muscle weakness ... of movement, Deafness ... Carpal timel syndrome ... hypertrophy, Proximal myopathy ... Signs #Symptoms #Diagnosis
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Anti-Synthetase Syndrome ... Mediated Necrotizing Myopathy ... Antibodies #MSAs #clinical ... #diagnosis #rheumatology ... #table
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