15 results
Idiopathic Inflammatory Myopathies - 
Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Immune-Mediated Necrotizing Myopathy ... Antisynthetase Syndrome ... #Idiopathic #Myopathy ... #Comparison #Managment ... #algorithm #Rheumatology
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
• Inflammatory myopathy ... hypothyroid-induced myopathy ... Statin-induced myopathy ... - Necrotizing myopathy ... #diagnosis #management
Idiopathic Inflammatory Myopathies (IIM's)

RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's)

 • Overlap Myositis
Any inflammatory myopathy ... antisynthetase syndrome ... Inflammatory myopathy ... IIMs #diagnosis #rheumatology ... #dermatology #Myopathy
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... anti-synthetase syndrome ... and anti-HMGCR myopathy ... Myositis #diagnosis #rheumatology
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Anti-Synthetase Syndrome ... Mediated Necrotizing Myopathy ... clinical #diagnosis #rheumatology
Cardiorenal Syndrome (CRS) Types
 • Type 1 - Acute CRS: Alteration of renal perfusion is the
Cardiorenal Syndrome ... Hypertension, CKD induced myopathy ... #Cardiorenal #Syndrome ... #CRS #Types #cardiology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
late-onset nemaline myopathy ... capillary leak syndrome ... • Schnitzler syndrome ... Differential #Diagnosis #hematology
2 Percent MACE Image - After calculating the risk for acute coronary syndrome, select the corresponding
acute coronary syndrome ... #Management #PatientInfo ... #Cardiology #ChestPain
1 Percent MACE Image - After calculating the risk for acute coronary syndrome, select the corresponding
acute coronary syndrome ... #Management #PatientInfo ... #Cardiology #ChestPain
3 Percent MACE Image - After calculating the risk for acute coronary syndrome, select the corresponding
acute coronary syndrome ... #Management #PatientInfo ... #Cardiology #ChestPain