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diagnosis associations diseases management table ana anca antibody antineutrophil antinuclear antinxp2 antinxp2dm dermatology dermatomyositis differential disease erythematosus hematology igg4 lupus
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in ... Rheumatology • ... others (RNP, aPL antibodies ... RheumOnePagers #Autoantibodies ... #Rheumatology #
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Autoantibodies and ... syndrome Anti-Scl ... Goodpasture's syndrome #Autoantibodies ... diagnosis #table #rheumatology ... #antibodies
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... scleroderma) - Anti-Scl ... polyangiitis without renal ... Antineutrophil #antibodies ... #diagnosis #rheumatology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
pancreas, biliary, renal ... serum lgE, no autoantibodies ... (antinuclear antibodies ... workup #treatment #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(HCV) • CLL & MBL ... macular Vasculitis) Autoantibodies ... vascular beds-renal ... , retinal, DVT, ... Paraproteinemias #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• Anti-Ro/SSA autoantibodies ... Non-autoimmune rheumatologic ... La, anti-Jo-1, SCL ... -70, RNP antibodies ... anticardiolipin antibodies
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
without these autoantibodies ... • Antibodies targeting ... dorsal part of the MCP ... • Clear cell renal ... diagnosis #management #rheumatology
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