9 results
diagnosis management hematology differential lupus monoclonal oncology sle anca antibodies antibody antineutrophil antinuclear antinxp2dm behcet comparison cryoglobulinemia cryoglobulinemic defects dermatology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
dL the ULN R - Renal ... /dL or CC < 40 ml ... M spike: • CML ... diseases, CML, ... MGUS #diagnosis #hematology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... scleroderma) - Anti-Scl ... polyangiitis without renal ... + 30-60% • Renal-limited ... antibodies #diagnosis #rheumatology
Renal involvement in 35% of mixed cryoglobulinemia vasculitis Associated with : • Absence of skin
Renal involvement ... Combined decr of C3 and ... /min • <60 mL/ ... TerrierBen #Renal ... Vasculitis #Management #Rheumatology
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
concentration: > 750ng/mL ... and probably < ... 1500ng/mL • Non-adherence ... Special cases (e.g. renal ... Measurement #SLE #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
disease (panuveitis, retinal ... aseptic meningitis), MCC ... involvement (uveitis or retinal ... Ocular: Giant retinal ... signs #symptoms #rheumatology
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
in non-muscle myosin ... renal failure ... vWF, factor V, and ... myelofibrosis and ... differential #diagnosis #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(HCV) • CLL & MBL ... Evans • ITP • Cl-NH ... vascular beds-renal ... , retinal, DVT, ... Paraproteinemias #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
findings (ANA, ... Non-autoimmune rheumatologic ... APLA/LAC: • Renal ... La, anti-Jo-1, SCL ... Erythematosus #Diagnosis #Rheumatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
dorsal part of the MCP ... • Clear cell renal ... three days #AntiNXP2DM ... #AntiNXP2 #Dermatomyositis ... diagnosis #management #rheumatology
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