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diagnosis cryoglobulinemia cryoglobulinemic hematology management oncology ana anca antibodies antibody antineutrophil antinuclear behcet differential disease diseases erythematosus gammopathies involvement lupus
Diagnosis of Cryoglobulinemia Vasculitis 1) Presence of cryoglobulin Circulating immunoglobulins that precipitate with cold temperature and dissolve
Cryoglobulinemia Vasculitis ... 3 types 2) Vasculitis ... arterioles) MONOCLONAL ... arthritis • Renal ... #Diagnosis #Rheumatology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Multiple Myeloma and Monoclonal ... dL the ULN R - Renal ... /dL or CC < 40 ml ... if this is is monoclonal ... MGUS #diagnosis #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Can Feature A Monoclonal ... Autoimmunity: • -MM/WM: Vasculitis ... Hypergammaglobulinemic macular Vasculitis ... , retinal, DVT, ... Paraproteinemias #Hematology
Renal involvement in 35% of mixed cryoglobulinemia vasculitis Associated with : • Absence of skin
Renal involvement ... cryoglobulinemia vasculitis ... TerrierBen #Renal ... Cryoglobulinemia #Vasculitis ... #Management #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... vasculitis) • ... vessel vasculitis ... refractory disease : monoclonal ... signs #symptoms #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
scleroderma) - Anti-Scl ... ANCA-Associated Vasculitis ... polyangiitis without renal ... vasculitis - MPO ... antibodies #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
ANCA-associated vasculitis ... Non-autoimmune rheumatologic ... APLA/LAC: • Renal ... La, anti-Jo-1, SCL ... Erythematosus #Diagnosis #Rheumatology
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