9 results
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
in non-muscle myosin ... cataracts, and renal ... #comparison #table ... #differential # ... diagnosis #hematology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects ... Epithelial #Inherited #Defects ... Kidney #Nephrology #Diagnosis ... #Differential # ... Table
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
with coagulation defects ... Elevated Liver tests, Low ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
with coagulation defects ... Elevated Liver tests, Low ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
diarrhea / IBD Renal ... - Genetic defects ... Hypomagnesemia #Differential ... #Diagnosis #Low ... #Magnesium #Table
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
Onset: Insidious/slow ... Inflammatory #Myopathies #differential ... #diagnosis #comparison ... #rheumatology # ... table
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
If the value is low ... , tests to detect ... WBC count and differential ... the presence of renal ... #Workup #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... Diagnosis Framework ... vasculitis) - Affects ... • Complement (Low ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... , lymphopenia, low ... #Rheumatology