27 results
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... ) Loop agents (eg ... Adenosine #Nephron #Pathophysiology ... Action #nephrology #pharmacology
Common sodium channel blockers which cause QRS widening.

Anticonvulsants: 
 - Carbamazepine 
Antidysrhythmics:  
 - Group
QRS #widening #ECG ... #EKG #Pharmacology ... Toxicology #Diagnosis #Differential
High Output Heart Failure - Pathophysiology and Differential Diagnosis
Obesity - Systemic Vasodilation, Vasoactive Adipokines
Arteriovenous Fistula -
Heart Failure - Pathophysiology ... and Differential ... - Congenital (e.g ... HeartFailure #CHF #Pathophysiology ... #Differential #
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
cytokine synthesis, e.g ... Immunosuppressant #Drugs #Pharmacology ... #Pathophysiology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
#hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology #
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Anticoagulants - Pathophysiology ... parenteral agents (e.g ... anticoagulant (e.g ... anticoagulant (e.g ... #Pharmacology #Pathophysiology
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
calcineurin inhibitors (e.g ... Sympathomimetics (e.g ... anticholinergic effects (e.g ... Medications #Drugs #pharmacology ... #differential #
Isocoria - Pupillary Defects - Differential Diagnosis Algorithm
Relative Afferent Pupil Defect
 • Optic Neuritis
 • Ischemic
Pupillary Defects - Differential ... dissociation) • Pharmacologic ... (e.g Opioids, Alcohol ... • Botulism Pharmacologic ... Pupils #Defects #Differential
Fibrinolysis. 
Fibrinolysis occurs when plasminogen is activated to plasmin under the influence of factors such as
anticoagulant drugs (e.g ... Fibrinolysis #Pathway #Pathophysiology ... #Plasminogen #Pharmacology
Hypoxia and Hypoxemia - Overview
Hypoxia - insufficient oxygen delivered to tissues to meet demands
Hypoxemia - low
stagnant hypoxia (e.g ... carrying capacity (e.g ... cannot use oxygen (e.g ... summary #pulmonary #differential ... diagnosis #causes #pathophysiology