11 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Normal CK - Myositis ... #Lupus #Erythematosus ... Musculoskeletal #Complications ... pathophysiology #signs
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... - Budd Chiari Syndrome ... #Lupus #Erythematosus ... Gastrointestinal #Complications ... pathophysiology #signs
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
pain • Extra-CNS complications ... positive NMO only): Myositis ... autoimmune disorders (Systemic ... lupus erythematosus ... neurology #symptoms #signs
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features of Systemic ... Demyelinating syndromes ... Glomerulonephritis Myositis ... #erythematosus ... #signs #symptoms
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Peri-operative Hyperthermia ... crisis (late sign ... • Serotonin syndrome ... Anesthesiology #Anesthesia #Checklist ... #Diagnosis #Management
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
• Myalgia • Myositis ... (GBS), systemic ... lupus erythematosus ... (LEMS), systemic ... myopathy #diagnosis #management
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia
Unexplained increase in ETCO2 AND tachycardia AND increased
rise is a late sign ... Change breathing system ... as indicated COMPLICATIONS ... Intraoperative #Checklist ... #Diagnosis #Management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
ischemia - Skin: erythematous ... Conjunctivitis, mucositis ... • Cogan Syndrome ... lupus erythematosus ... purpura: strong sign
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
central nervous system ... neuritis • Partial myelitis ... • Or brainstem syndromes ... • Lhermitte’s sign ... sclerosis #diagnosis #management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... ischemia • Skin: Erythematous ... Conjunctivitis, mucositis ... vasculitis • Behcet syndrome ... vasculitis • Cogan syndrome