18 results
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
positive NMO only): Myositis ... autoimmune disorders (Systemic ... lupus erythematosus ... , Sjögren syndrome ... neurology #symptoms #signs
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features of Systemic ... Demyelinating syndromes ... Glomerulonephritis Myositis ... #erythematosus ... #signs #symptoms
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... anemia 4% - Myositis ... (aPL) 30-45% Differential ... #Lupus #Erythematosus ... autoantibodies #signs
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
lupus erythematosus ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... , Myositis, Mixed ... rheumatology #diagnosis #differential
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Peri-operative Hyperthermia ... crisis (late sign ... #Differential # ... Anesthesiology #Anesthesia #Checklist ... #Diagnosis #Management
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... central nervous system ... Peripheral Nervous System ... Lack of UMN/LMN signs ... #Weakness #Differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... Neuropsychiatric systemic ... • Transverse Myelitis ... papillomavirus #SLE #Systemic
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
• Myalgia • Myositis ... (GBS), systemic ... lupus erythematosus ... (LEMS), systemic ... myopathy #diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... ischemia - Skin: erythematous ... Conjunctivitis, mucositis ... lupus erythematosus ... purpura: strong sign
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Allopecia - Differential ... Discoid lupus erythematosus ... , Loose anagen syndrome ... Examination: • Signs ... Vitamin D levels Systemic