23 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Proximal tubule Bartter ... loop of Henle Gitelman ... #Fanconi #Bartter ... Nephron #Defects #Pathophysiology ... #Nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
thiazide diuretics, Bartter ... syndrome, Gitelman ... syndrom, Vomiting ... Diagnosis #Algorithm #causes ... potassium #low #nephrology
Hypomagnesemia - Differential Diagnosis
Renal Causes of Hypomagnesemia - Familial:
Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
Diagnosis Renal Causes ... Hypomagnesemia - Familial: Bartter ... syndrome and Gitelman ... syndrome, Isolated ... #nephrology #magnesium
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... Syndrome Volume ... Diagnosis #Algorithm #Nephrology ... #Causes
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
- Gitelman ... syndrome - ... Low #Magnesium #Table ... Classification #Causes ... #Workup #hypomg
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... Defining the cause ... • Diuretics, Bartter's ... syndrome, Gitelman's ... #nephrology #potassium
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
acid transporter Bartter ... syndrome - Na-K ... ascending limb Gitelman ... Defects #Kidney #Nephrology ... #Differential #Table
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
wasting from other causes ... suggests extra-renal causes ... Emesis, Diuretics, Bartter ... syndrome, Gitelman ... differential #potassium #nephrology
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
acid, Liddle's Syndrome ... h - Diuretics, Bartter's ... syndrome, Gitelman's ... Diagnosis #Algorithm #nephrology ... #causes #low #potassium
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... • Bartter syndrome ... • Pseudo Bartter-Gitelman ... #nephrology #management ... #pathophysiology