21 results
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... water Extrarenal hypotonic ... salt intake: • Hypertonic ... Differential #Diagnosis #Causes ... #nephrology #sodium
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
Physiologic Approach to Hypotonic ... of hypotonic hyponatremia ... : Hypovolemia, Hypervolemia ... #Physiologic #Hypotonic ... differential #diagnosis #table
Hyponatremia - Differential Algorithm
Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP
Hypotonic Hyponatremia: 
 • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
, Recent TURP Hypotonic ... polydipsia • Hypervolemia ... Hypothyroidism Hypertonic ... Algorithm #diagnosis #causes ... #nephrology #sodium
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Sodium zirconium ... constipation, diarrhea, nausea ... ); nausea, vomiting ... #medications #pharmacology ... #table #comparison
Emergency Therapy of Hyperkalemia
Therapy - Dose and Route - Onset of Action - Duration of Effect
Emergency Therapy of Hyperkalemia ... glucose, Furosemide, Sodium ... Hemodialysis #Hyperkalemia ... #management #pharmacology ... #table #treatment
Treatment of Hyperkalemia
Membrane Stabilization
 • Calcium Gluconate (10%)
 • Hypertonic (3%) Normal Saline
Shifters:
 • Insulin (Short
Treatment of Hyperkalemia ... Gluconate (10%) • Hypertonic ... Furosemide • Sodium ... Bicarbonate • Sodium ... Interventions #Table
Etiologies of Hypernatremia - Differential Diagnosis
GI losses / Insensible losses
Sodium Overload
Transcellular Movement of Water
Central Diabetes Insipidus
Insensible losses Sodium ... cisplatin) - Chronic hypercalcemia ... - Chronic hypokalemia ... Differential #Diagnosis #Table ... #Causes
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Management of Hyperkalemia ... • SPS - Sodium ... veltassa) • SZC - Sodium ... #treatment #pharmacology ... #table #comparison
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... intracellular calcium causes ... - Hyperkalemia ( ... , in states of hypokalemia ... CaitEKulig #Digoxin #Pharmacology
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
while retaining sodium ... , which causes increased ... because of the sodium ... avoid harmful hyperkalemia ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology