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differential rheumatology infections neurology treatment disorders erythematosus fungal lupus oncology pulmonary signs sle symptoms systemic abg acid acidbase activation aids
Multiple Cranial Neuropathies - High Yield Differential Diagnosis • Intrinsic brainstem process • Compressive brainstem process
Yield Differential Diagnosis ... Neurosarcoidosis • CNS ... Miller Fisher Syndrome ... • Myasthenia Gravis ... #causes
Localizing Extraocular Movement Disorders • CN Ill (Oculomotor) Nerve Palsy • CN IV (Trochlear) Nerve
One-and-a-half Syndrome ... Cavernous Sinus (CS ... Skew Deviation Casey ... #differential #diagnosis ... #ocular
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
desaturation, Scotoma, Ocular ... involvement: Intractable nausea ... pain • Extra-CNS ... , Myasthenia gravis ... Manifestations #diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
basal ganglia, CNS ... meningitis), MCC CNS ... collaboration • CNS ... #diagnosis #management ... signs #symptoms #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... autoantibodies that will cause ... Erythematosus #SLE #CNS ... #management #treatment
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Scleromyxedema (CNS ... Hypergammaglobulinemic macular ... Ravi Singh @rav7ks ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Ocular- 50%: Ptosis ... muscles: “myasthenic crises ... myasthenia Diagnosis ... Myasthenia Crises ... #diagnosis #management
Causes of Antibiotic Failure - Differential Diagnosis Framework Diagnosis: • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Causes of Antibiotic ... Framework Diagnosis ... , serotonin syndrome ... Tissue penetration (CNS ... , prostate, ocular
Guillain–Barré syndrome (GBS) (aka: Landry–Guillain–Barré–Strohl syndrome:  Most common cause of acute flaccid paralysis  Rapidly progressive ascending paralysis & areflexia  Autonomic
Guillain–Barré syndrome ...  Most common cause ... Differential diagnosis ...  Myasthenia gravis ... Multiple Sclerosis: CNS
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
gland) biopsy • Ocular ... Parotid swelling CNS ... nervous system (CNS ... • 8%-27% for CNS ... Diagnosis #Management
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