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diagnosis rheumatology syndrome betadglucan galactomannan hematology infectiousdiseases neurology skin treatment abscess adultonset arteritis aspergillus biomarkers causes classification comparison dermatologic disease
Differential diagnosis of Skin + Eye infections • Bacterial: Staph spp, Strep spp, Pseudomonas spp, Bartonella,
Differential diagnosis ... of Skin + Eye infections ... ] #skin #eye #ocular ... #dermatology #InfectiousDiseases ... #Infections #Differential
Kerion Raised, boggy lesion with heaped up purulent nodules Caused by host's response to a fungal ringworm
response to a fungal ... ringworm infection ... mentagrophytes) Clinical ... Griseofulvin #Kerion #Dermatology ... #Diagnosis #Management
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
infection (IFI) ... cut-offs defined in clinical ... surfaces - Infections ... BAL GM does not differentiate ... - Frozen ice-pops
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... reticularis Differential ... cell arteritis Infections ... Mycobacterial diseases • Fungal ... infections (histoplasmosis
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... fraction < 20% Differential ... Diaqnoses: • Infectious ... • Ocular: uveitis ... Disease #diagnosis #management
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
cut-offs defined in clinical ... surfaces, Albumin, Infections ... >90% (In most clinical ... in BAL does not differentiate ... Penicillium), Frozen ice-pops
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Ocular- 50%: Ptosis ... life-threatening Differential ... Bedside: ice pack ... precipitated by: Drugs, infection ... Gravis #diagnosis #management
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
polymicrobial infection ... Lung Abscess - Clinical ... Prevotella • Fungal ... Lung Abscess Differential ... Abscess #pulmonary #differential
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
Diagnosis and Management ... than 1500 and clinical ... hypersensitivity - Infection ... : helminthic, fungal ... #differential #
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Direct microbial infection ... Transverse Myelitis - Clinical ... Herpes zoster, West Nile ... Myelitis #diagnosis #management ... #neurology #differential
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