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diagnosis lupus differential disease erythematosus symptoms syndrome classification hematology stills vasculitis workup activation adultonset ana anesthesia anesthesiology antibodies antinuclear aosd
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... (SLE) General: ... of hip (rare), Arthritis ... #signs #symptoms ... #diagnosis #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome Systemic ... Epidemiology: • Young adults ... Syndrome #diagnosis #management ... #signs #symptoms ... #rheumatology #
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... Fever, Arthralgia/arthritis ... solid cancers • Systemic ... • Ocular: uveitis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
33% of healthy adults ... likely it will be clinically ... Juvenile Idiopathic Arthritis ... Juvenile Idiopathic Arthritis ... ANA #patterns #rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
vasculitis in older adults ... Diagnosis = clinical ... Nice to be confident ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Erythematous, macular ... , adult-onset Still ... Non-autoimmune rheumatologic
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Erythematosus Clinical ... cutaneous lupus • Arthritis ... Classification #Criteria #SLE ... Erythematosus #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
(sJIA) • Adult-onset ... Fever is the main clinical ... erythematosus [SLE ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms, Arthritis ... months to years) Systemic ... 40, F:M 9:1 • Clinical ... comparison #table #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
ulcers, cutaneous, ocular ... Syndrome: - Ocular ... purpura: strong sign ... vasculitis, and SLE ... differential #diagnosis #rheumatology
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