13 results
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... diseases: - 10% SLE ... RA - 5 to 20% Sjögren's ... erythematosus (SLE ... classification #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Systemic Lupus (SLE ... Butterfly rash, Vasculitis ... Demyelinating syndromes ... symptoms #diagnosis #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... (Clinical Dx). ... Oral aphthae : SLE ... #diagnosis #management ... signs #symptoms #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
- SLE Neurologic ... Lyme disease, Vasculitis ... , Behçet's syndrome ... enlargement - Sjögren's ... differential #diagnosis #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... overlaps with RA, SLE ... gland) biopsy • Ocular ... salivary ducts Clinical ... #Syndrome #Rheumatology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Autoimmune: thyroid, Sjogren ... arthritis, SLE ... Ocular- 50%: Ptosis ... Gravis #diagnosis #management ... #neurology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Erythematous, macular ... dermatomyositis, Sjogren ... Non-autoimmune rheumatologic ... Clinical Features
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
diseases, such as SLE ... affects the skin, neurologic ... cognitive impairment, neurologic ... • Cogan syndrome ... Differential #Diagnosis #Rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
) Clinical Manifestations ... Demyelinating Syndrome ... #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... or Sjogren's ... - Vasculitis- ... Myelitis #diagnosis #management ... #neurology #differential