11 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
of Systemic Lupus ... Erythematosus (SLE ... ) Clinical Manifestations ... Erythematosus #SLE ... #CNS #neurology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome Systemic ... association • M > F Clinical ... skin injury) • Neurologic ... Oral aphthae : SLE ... • Arthritis: SLE
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Erythematosus Clinical ... least 2 joints • Neurologic ... Classification #Criteria #SLE ... Erythematosus #diagnosis
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... desaturation, Scotoma, Ocular ... autoimmune disorders (Systemic ... Manifestations #diagnosis ... #neurology #symptoms
Headache Etiologies and Associated Spectrum of Severity of Disease by System
Critical, Emergent and Non-Emergent Causes
CNS, neurologic,
of Disease by System ... Critical, Emergent ... Non-Emergent Causes CNS ... vascular disease Ocular ... #differential #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Erythematous, macular ... Differential Diagnosis ... Erythematosus #Diagnosis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... diseases, such as SLE ... affects the skin, neurologic ... cognitive impairment, neurologic ... chorioretinitis, CNS
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
rheumatoid arthritis, SLE ... Ocular- 50%: Ptosis ... myasthenia Diagnosis ... Bedside: ice pack ... #management #neurology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Sjogren's Syndrome Diagnosis ... gland) biopsy • Ocular ... salivary ducts Clinical ... Central nervous system
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... Transverse Myelitis - Clinical ... Evaluate for NMO, SLE ... Disorders: - SLE ... #management #neurology