29 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... Differential Diaqnoses ... mevalonate kinase deficiency ... • Ocular: uveitis ... #treatment #rheumatology
Korsakoff Syndrome
Clinical Findings:
 • Confabulation: Usually initial phase of the disease
 • Anterograde amnesia: Memory impairment
Clinical Findings ... initial phase of the disease ... presentation of Thiamine deficiency ... Encephalopathy Treatment ... #neurology #diagnosis
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Thiamine Deficiency ... - Differential Diagnosis ... Framework and Clinical ... #Differential #Diagnosis ... #nutrition #pathophysiology
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
may cause severe clinical ... due to chronic disease ... hyperparathyroidism Treatment ... #Differential #Diagnosis ... #Pathophysiology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... ulceration • Ocular ... (Clinical Dx). ... ) Differential Diagnosis ... Arthritis, AS Treatment
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Differential Diagnosis ... Myeloproliferative disease ... • Nephrotic Syndrome ... fibrillation - Left ventricular ... Venous #Arterial #pathophysiology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Clinical Picture ... Ocular- 50%: Ptosis ... myasthenia Diagnosis ... Bedside: ice pack ... Myasthenia #Gravis #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... • Autoimmune diseases ... Cellular immune deficiency
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Cerebrovascular Disease ... , PRES Pathophysiology ... permeability Diagnosis
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Scurvy (Vitamin C Deficiency ... ) - Diagnosis and ... poor nutrition Clinical ... • Delusions Ocular ... vasculitis Treatment