16 results
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Acute Rheumatic ... B and CD-4+ T cells ... pathophysiology #diagnosis ... #signs #symptoms ... #complications
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Diagnosis: • ... ’s lymphoma or acute ... Contamination, colitis
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
cells -> Mutagenic ... Retinoblastoma Signs ... / Symptoms / Complications ... ophthalmology #diagnosis ... #signs #symptoms
Acute Otitis Media: Complications
Infection and inflammation of the middle ear
 - Prolonged obstruction of e. tube
Acute Otitis Media ... to mastoid air cells ... becomes more severe Signs ... /Symptoms/Complications ... #signs #diagnosis
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... Consider stem cell ... neutropenic fever) Complications ... progress to MDS or acute
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
• Langerhan cells ... UV light Incr cell ... pathophysiology #diagnosis ... #signs #symptoms ... #complications
Clinical Manifestations of Sickle Cell Disease

Anaemia
Infection
Painful crises
Priapism
Splenomegaly
Long Term Problems - Short stature and delayed puberty, Stroke
Manifestations of Sickle Cell ... Splenomegaly Long Term ... SickleCell #Disease #Signs ... #Symptoms #Diagnosis
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
polymorphisms alter cell-mediated ... various inflammatory cells ... histopathologic term ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
clinical findings Acute ... ) Stage 4: Cell ... larger & irregular cavities ... pathophysiology #signs ... #symptoms #diagnosis
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
and ophthalmic complications ... systemic sx + signs ... absence of visual symptoms ... GCA #Temporal #Signs ... #Symptoms #Diagnosis