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complications differential vasculitis acute avascularnecrosis bulimianervosa causes chronic cll gait hematology henochscholeinpurpura iga leukemia lupus lymphocytic management manifestations mastoiditis msk
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
histopathologic term ... response) - Cutaneous ... and ankles) #HSP ... #Diagnosis #Signs ... #Symptoms
Trendelenburg Gait: Pathogenesis and clinical findings Skeletal Pathology of the Hip • Arthritis • Congenital hip dysplasia
• Congenital hip ... valga • Slipped capital ... Trendelenburg #Gait #pathophysiology ... #causes #symptoms ... #signs #diagnosis
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
B and CD-4+ T cells ... Prolonged PR Interval, Carditis ... RheumaticFever #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
• Langerhan cells ... response -> Subacute cutaneous ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
• Plasma cells ... Extra-articular signs ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms ... #diagnosis
Mastoiditis: Pathogenesis and clinical findings Acute or Chronic Otitis Media -> Stage 1: Hyperemeia of the mastoid
the mastoid air cells ... larger & irregular cavities ... #Mastoiditis #pathophysiology ... #signs #symptoms ... #diagnosis #otology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Agent Orange or Hep ... with no early symptoms ... Physical Exam/Signs ... phenomenon CLL Diagnosis ... Contamination, colitis
Avascular Necrosis: Pathogenesis and Clinical Findings • Physical Trauma (esp. to the scaphoid bone with damage
hematopoietic marrow cells ... hypolucency "Crescent sign ... AvascularNecrosis #pathophysiology ... #diagnosis #signs ... #symptoms
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... Presentation: Systemic Symptoms ... purpura: Strong sign ... of shoulder and hip ... • Progressive symptoms
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... • Bilateral signs ... and/or symptoms ... Pleocytosis > 100 cells ... simplex virus, HIV, Hep
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