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hematology hepatology causes injury anemia lfts acute agglutinin cold disease extravascular gap globulin hemolytic hepatocellular intravascular liverenzymes mcv myopathy myositis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... : Autoimmune hepatitis ... extrahepatic source - Tests ... diagnosis #algorithm
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... Diagnosis Hepatocellular ... C, A, E, B, D, EBV ... Other: NAFLD, Autoimmune ... #Acute #algorithm
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential ... Diagnosis Algorithm ... Cold AIHA • PCH ... • PNH ... #Diagnosis #Algorithm
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Membrane): - Autoimmune ... Defects, Drugs, Liver ... Disease, PNH ... Laboratory Tests
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
→ liver test abnormalities ... A/B/C/D/E, EBV, ... Other: NAFLD, Autoimmune ... #algorithm #Transaminitis ... #LFTs #hepatitis
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... Diagnosis Framework ... PK, HbC, HbSS, PNH ... - Extrinsic: Autoimmune ... Non-megaloblastic: Liver
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Diagnosis Algorithm ... • Ischemia • Autoimmune ... • Alcoholic hepatitis ... #Diagnosis #Algorithm
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral infection, autoimmune ... Diagnosis: • hemolytic ... - Mycoplasma, EBV ... younger pts) Differential ... test #cold #
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Sarcoidosis) • Liver ... Cirrhosis, ETOH, autoimmune ... hepatitis, PBC, ... PSC, Viral hepatitis ... #diagnosis #hematology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... Tests: • Measure ... • ANA < 20 % IBM ... , autoimmune hepatitis ... #rheumatology #differential
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