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diagnosis hepatology algorithm injury hematology lfts transaminitis acute aids cmv cytomegalovirus elevated gap globulin hemolysis hepatocellular hiv liverenzymes myopathy myositis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... C, A, E, B, D, EBV ... Other: NAFLD, Autoimmune ... #Diagnosis #Causes
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Algorithm Vascular Causes ... HBV, HCV, HEV, EBV ... : Autoimmune hepatitis ... extrahepatic source - Tests
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Transaminitis - Differential ... HAV, HCV, HEV, EBV ... Trauma: Shock liver ... obstruction syndrome • Autoimmune ... Diagnosis #causes
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
test abnormalities ... • Infections: Hepatitis ... A/B/C/D/E, EBV, ... Other: NAFLD, Autoimmune ... Transaminitis #LFTs #hepatitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... • Ischemia • Autoimmune ... • Alcoholic hepatitis ... Diagnosis #Algorithm #Causes
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Membrane): - Autoimmune ... Drug-associated, PCH ... Defects, Drugs, Liver ... Disease, PNH ... Laboratory Tests
Cytomegalovirus (CMV) in HIV-AIDS Patients Cytomegalovirus (CMV): double-stranded DNA virus, herpesvirus family. CMV infection: virus isolation or detection
pp65 antigenemia test ... Retinitis (Most common cause ... blindness in AIDS) • Liver ... : Hepatitis, Portal ... AIDS #diagnosis #differential
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Sarcoidosis) • Liver ... Cirrhosis, ETOH, autoimmune ... hepatitis, PBC, ... PSC, Viral hepatitis ... Gap #ProteinGap #differential
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... Diagnostic Tests ... • ANA < 20 % IBM ... statins - probably caused ... , autoimmune hepatitis
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