17 results
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
- Pharmacology ... • Euglycemic diabetic ... #Pharmacology # ... Summary #DM2 #diabetes ... #endocrinology
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Medication Guide Classes ... mealtime • If NPO ... #Mellitus #DM2 ... #Medications #pharmacology ... comparison #table #endocrinology
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology ... not definitively cause ... #Pharmacology # ... Summary #DM2 #diabetes ... #endocrinology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
These work by inhibiting ... kidney), which causes ... #Pharmacology # ... Medications #DM2 ... #Diabetes #Endocrinology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... agent • Does not cause ... #Metformin #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
DPP4 Inhibitors ... work by increasing ... Renal #Dosing #Pharmacology ... #Management #Diabetes ... #DM2 #Endocrinology
Causes of Polyuria - Differential Diagnosis
Excess Intake of Water:
 • Primary polydipsia (a.k.a. "psychogenic polydipsia")
 •
Causes of Polyuria ... - Differential ... mellitus, SGLT2 inhibitors ... Diabetes Insipidus ... volume): • UTI, BPH
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
- Proton-pump inhibitors ... - Uncontrolled diabetes ... Hypomagnesemia #Differential ... Classification #Causes ... #Workup #hypomg
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
to treat Type 2 Diabetes ... They work primarily ... GLP1 #Agonists #Pharmacology ... #Dosing #Diabetes ... #DM2 #Endocrinology
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Hyperuricemia - Differential ... Hyperparathyroidism • Diabetic ... drugs • ACE inhibitors ... Diagnosis #Algorithm #endocrinology ... #causes