2764 results
NSAID Pharmacology

- Amy Chung, MD, MSc @AmyChung 

#NSAIDs #Pharmacology #COX #Cyclooxygenase
NSAID Pharmacology ... @AmyChung #NSAIDs
NSAID Selectivity Spectrum
COX-2 Selective NSAID - Celecoxib
 • Increased risk for CV events
 • Decreased risk
NSAID Selectivity ... COX-2 Selective NSAID ... Semiselective NSAIDs ... risk Nonselective NSAIDs ... side effects #NSAIDs
NSAID vs ACEI/ARB effects on the Kidneys

Remember that NSAIDs and ACEI/ARB therapy have opposing effects on
NSAID vs ACEI/ARB ... Remember that NSAIDs ... NSAIDs cause vasoconstriction ... kidney function, NSAID ... /ambcarerx #NSAIDs
Anticoagulation Review. There are other bleeding risk assessment tools, but HAS-BLED is more commonly used. HTN
There are other bleeding ... Bleeding includes ... that increase bleeding ... antiplatelets or NSAIDs ... Anticoagulant #Bleeding
Forrest Classification for Peptic Ulcer Bleeding
Rebleeding risks are without endoscopic intervention
1a - Spurting Bleed - 60-100%
for Peptic Ulcer Bleeding ... Bleed - 60-100% Re-bleeding ... Bleed - 50% Re-bleeding ... IIa - Non-Bleeding ... Clot - 20-30% Re-bleeding
Adverse Effects of NSAIDs
Prostaglandins decreased
 - Gastric mucosal damage with ulcer formation, bleeding, and perforation
 -
Adverse Effects of NSAIDs ... ulcer formation, bleeding ... proinflammatory effect #NSAIDs
Forrest Classification for Describing Endoscopic Findings in Patients With Bleeding Ulcers and Predicting Risk of Rebleeding

Classification
Patients With Bleeding ... Predicting Risk of Rebleeding ... Diet I Active bleeding ... II Stigmata of bleeding ... Endoscopy #EGD #Risk #Rebleeding
CERTA Opioid Alternatives

Opioid Alternatives for Abdominal Pain (traumatic, non-traumatic), Back Pain, Burns, Renal Colic, Dental Pain,
DO NOT mix NSAID ... Caution with using NSAIDs ... contraindications for NSAID
Prosthetic Mitral Valve Endocarditis - No bueno!

- Dr. Said Alsidawi @AlsidawiMD

#Prosthetic #MitralValve #Endocarditis #Echocardiogram #POCUS #Clinical
Said Alsidawi @AlsidawiMD ... Echocardiogram #POCUS
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
first variceal bleeding ... Prevention of variceal rebleeding