14 results
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy
 • Central or peripheral neurologic disease
Proximal Muscle Weakness ... disease • Myasthenia ... gravis • Muscular ... mimics #diagnosis #differential ... #causes #neurology
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Sensory Changes - Differential ... Cardio-pulmonary disease ... • Endocrine Disease ... • Congenital Myopathy ... #Neurology #Differential
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Motor Nerves: ALS ... Mitochondrial myopathy ... , Muscular dystrophy ... #Causes #differential ... #diagnosis #neurology
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
- Differential ... Bacteremia, Sepsis • Kidneys ... I am weak": • Myopathy ... Polyneuropathy, ALS ... Diagnosis #causes #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... Lack of UMN/LMN signs ... Myopathy: ... #Differential # ... Diagnosis #neurology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Cord Disorders - Differential ... • Symptoms and signs ... Sarcoidosis, Behcet disease ... disorders #diagnosis #neurology ... #differential
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Presentation: - Disease ... course of the disease ... 4) progressive muscular ... conditions listed in differential ... Lateral #Sclerosis #neurology
Ptosis - Differential Diagnosis Framework

Ptosis (Greek- to fall) Drooping of the upper eyelid that usually results
Ptosis - Differential ... disease affecting ... to ptosis and weakness ... Oculopharyngeal muscular ... Syndrome #Ptosis #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
life-threatening Differential ... Generalized fatigue - ALS ... - Peek sign ... : Steroids and NSAIDs ... diagnosis #management #neurology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... papules and Gottron sign ... ) • Shawl sign ... /muscular atrophy ... : • PBC, autoimmune