10 results
Diabetes Combination Tablets - Estimated A1c Lowering 
Metformin + DPP4 
• Janumet (metformin + sitagliptin) 
•
Diabetes Combination ... + DPP4 • Janumet ... dapagliflozin) Dpp4 ... Tablets #Oral #DM2 ... #Pharmacology #
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
Action for Common Diabetes ... • Biguanides (Metformin ... GLP-1 Receptor Agonists ... • DPP4i / Gliptins ... #Medications #pharmacology
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
Diabetes Medications ... modifications Metformin ... GLP-1 receptor agonists ... events TZDs DPP ... endocrinology #dm2
Oral Hypoglycemics in Diabetes Management
1  INSULIN SENSITIZER
 • TZD 
     -
- PPAR gamma agonist ... Sensitivity - Metformin ... (Adlyxin) • DPP ... #Management #pharmacology ... #DM2 #DMII #Classification
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology ... GLP-I receptor agonist ... #Inhibitors #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
Metformin - First Line Treatment for Diabetes Type 2
• Start with initial dose of 500 mg
Metformin - First ... Treatment for Diabetes ... form and consider using ... Indications #Titration #Pharmacology ... #Diabetes #DM2
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Normal and Renal Dosing ... Inhibitors #Renal #Dosing ... #Pharmacology # ... Management #Diabetes ... #DM2 #Endocrinology
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
GLP-1 Agonists ... to treat Type 2 Diabetes ... very similar to DPP4s ... #Pharmacology #Dosing ... #Diabetes #DM2
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Diabetes Mellitus ... Sulfonylurea, TZD, DPP ... GLP-1 receptor agonist ... #Mellitus #DM2 ... #Medications #pharmacology
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist
Dosing:
3 mg daily x 30 days, then 7 mg
Dosing: 3 mg ... oral route by using ... empagliflozin and DPP4 ... #semaglutide #Diabetes ... #Pharmacology #