11 results
Daptomycin  - Antibiotics Class Overview

Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Daptomycin - Antibiotics ... No gram negative ... skin/soft tissue infections ... MRSA bacteremia/endocarditis ... #Review #Overview
Aminoglycosides  - Antibiotics Class Overview

Gentamicin, Tobramycin, Amikacin, Streptomycin -30S inhibitor (all IV)
Spectrum: Extremely efficacious vs.
Aminoglycosides - Antibiotics ... . aerobic Gram negatives ... infections especially ... effect (mainly in endocarditis ... #Review #Overview
Capnocytophaga
Pathogen: Capnocytophaga
 • 9 species, C. canimorsus responsible for the majority of infections
 • Gram-negative rod,
9 species, C. canimorsus ... the majority of infections ... • Gram-negative ... 13%), Pneumonia, Endocarditis ... microbiology #zoonotic #infectiousdiseases
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
gram-negative bacillus ... to meningitis, endocarditis ... Myocarditis & culture-negative ... infection, because ... or clindamycin Antibiotic
Coverage of common antibiotics used in the hospital

For empiric coverage, first define the type of infection,
define the type of infection ... , then review prior ... Consult ID if needed ... #management #infectiousdisease ... #antibiotics
CAPD-associated peritonitis (Continuous Ambulatory Peritoneal Dialysis) - 5 Things To Know
Diagnosis (Two of the following):
(1) Clinical
diverticulitis) Treatment ... Conncomitant catheter infection ... • Prophylactic antibiotics ... Washington University ID ... Diagnosis #Management #InfectiousDiseases
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... Infective Endocarditis ... Work-up of BCNIE relies ... #Infective #Endocarditis ... differential #workup #infectiousdiseases
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
aureus, Coagulase-negative ... staphylococci Culture Negative ... hematuria, + RF Treatment ... • IV antibiotics ... Diagnosis #cardiology #infectiousdiseases
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Histoplasmosis Treatment ... nonspecific • DX relies ... Mucormycosis Treatment ... arthritis, and endocarditis ... ) #Mycoses #InfectiousDiseases
Sulfonamides - Antibiotics Class Overview

BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic

Spectrum: Wide
Sulfonamides - Antibiotics ... and most Gram negatives ... choice, both for treatment ... #Pharmacology #Antibiotics ... #Review #Overview