13 results
Daptomycin  - Antibiotics Class Overview

Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Daptomycin - Antibiotics ... Class Overview ... No gram negative ... MRSA bacteremia/endocarditis ... #Review #Overview
Aminoglycosides  - Antibiotics Class Overview

Gentamicin, Tobramycin, Amikacin, Streptomycin -30S inhibitor (all IV)
Spectrum: Extremely efficacious vs.
Aminoglycosides - Antibiotics ... Class Overview ... . aerobic Gram negatives ... effect (mainly in endocarditis ... #Review #Overview
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures
 - Did they receive antibiotics prior
with Infective Endocarditis ... Did they receive antibiotics ... Decreased yield due to antibiotic ... #Infective #Endocarditis ... #Diagnosis #Management
Campylobacter
Clinical 
 • Fever 
 • Abdominal pain 
 • Diarrhea (bloody stools) 
 • Vomiting
self-limited) • Antibiotics ... Fluoroquinolones, azithromycin ... Campylobacter #Diagnosis ... #Management #Overview
Infective endocarditis - etiology and sources of infection. 
 • Native and prosthetic 
valve endocarditis
 •
Infective endocarditis ... • Native and ... prosthetic valve endocarditis ... for TPN) and antibiotic ... #Microbiology #Diagnosis
Macrolides - Erythromycin, Clarithromycin, Azithromycin - Antibiotics Class Overview

50S Ribosomal Inhibitor (PO and IV)
Spectrum: Atypical organisms
- Antibiotics Class ... Overview 50S ... and some gram negatives ... #Pharmacology #Antibiotics ... #Review #Overview
Endocarditis checklist
Initial evaluation
 • Peripheral blood cultures (three sets at three different sites)
 • Additional culture
Endocarditis checklist ... suspect right-sided endocarditis ... course • Adjust antibiotics ... #checklist #criticalcare ... #diagnosis #management
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
bacilliformis: - Gram negative ... Nodular → Mular DIAGNOSIS ... Supportive and antibiotics ... : rifampicin + azithromycin ... #Oroya #Fever #diagnosis
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
• Coagulase-negative ... Differential Diagnosis ... Diagnosis? ... • IV Antibiotics ... #diagnosis #management
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
Endocarditis - Overview ... and Differential Diagnosis ... aureus, Coagulase-negative ... staphylococci Culture Negative ... Treatment • IV antibiotics