12 results
Daptomycin  - Antibiotics Class Overview

Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Daptomycin - Antibiotics ... Class Overview ... Mechanism: Lipopeptide antibiotic ... No gram negative ... #Review #Overview
Carbapenems - Antibiotics Class Overview

Imipenem/Cilastin, Meropenem, Ertapenem, Doripenem 

Spectrum: Broadest spectrum antibiotics, cover Gram positive, Gram
Carbapenems - Antibiotics ... Class Overview ... positive, Gram negative ... resistant gram negatives ... #Review #Overview
Aminoglycosides  - Antibiotics Class Overview

Gentamicin, Tobramycin, Amikacin, Streptomycin -30S inhibitor (all IV)
Spectrum: Extremely efficacious vs.
Aminoglycosides - Antibiotics ... Class Overview ... . aerobic Gram negatives ... : serious gram negative ... #Review #Overview
Tigecycline (IV) - Antibiotics Class Overview

Mechanism: Glycylcycline class - structurally related to Tetracyclines (bacteriostatic).  Only
Tigecycline (IV) - Antibiotics ... Class Overview ... and VRE), Gram negatives ... #Pharmacology #Antibiotics ... #Review #Overview
Vancomycin and Dalbavancin (lipoglycopeptide antibiotics) - Antibiotics Class Overview

Mechanism: Glycopeptide -  inhibits cell wall synthesis
lipoglycopeptide antibiotics ... ) - Antibiotics ... Class Overview ... No gram negative ... #Review #Overview
Monobactam - Aztreonam - Antibiotics Class Overview

Spectrum: only has activity vs. aerobic gram negatives, no gram
- Aztreonam - Antibiotics ... Class Overview ... . aerobic gram negatives ... due to gram-negative ... #Review #Overview
Tetracyclines – Doxycycline, Tetracycline, Minocycline - Antibiotics Class Overview

- 30S Inhibitors (PO and IV)
Spectrum: Fairly broad
Minocycline - Antibiotics ... Class Overview ... coverage, some gram negative ... #Pharmacology #Antibiotics ... #Review #Overview
Macrolides - Erythromycin, Clarithromycin, Azithromycin - Antibiotics Class Overview

50S Ribosomal Inhibitor (PO and IV)
Spectrum: Atypical organisms
Azithromycin - Antibiotics ... Class Overview ... and some gram negatives ... #Pharmacology #Antibiotics ... #Review #Overview
Sulfonamides - Antibiotics Class Overview

BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic

Spectrum: Wide
Sulfonamides - Antibiotics ... Class Overview ... and most Gram negatives ... #Pharmacology #Antibiotics ... #Review #Overview
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
Endocarditis - Overview ... aureus, Coagulase-negative ... staphylococci Culture Negative ... Treatment • IV antibiotics