19 results
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
NEJM 1999 - ICU FOCUS ... Transfusing blood ... Blood saves lives ... unnecessary and cause ... Transfusion #Thresholds #Hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
which can plug blood ... levels >1g/L • Negative ... causes of secondary ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... TRALI): Leading cause ... more likely to cause ... Transfusion #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Causes purpura & ... TRALI): Leading cause ... more likely to cause ... Transfusions #diagnosis #management ... #hematology #reactions
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
decrease in most cases ... of Peripheral blood ... antiglobulin tests - Negative ... hematuria (without casts ... Diagnosis #Workup #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... Drugs, Unknown cause ... Nicolas Taar ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Intraoperative Laryngospasm and Stridor - Guidelines for Crises in Anaesthesia

❶ Call for help and inform theatre
inform theatre team ... suction catheters, blood ... oxygen and face mask ... has developed negative-pressure ... Checklist #Diagnosis #Management
ECMO Troubleshooting - OnePager Summary
ECMO Emergency Protocol - Team should train/practice & have necessary supplies at
Emergency Protocol - Team ... circuit and can cause ... bleed, and reduced blood ... EMBOLISM - can cause ... #differential #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... Treat primary cause ... Coagulation #diagnosis #causes ... #treatment #management ... #hematology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
in the US each year ... a five to ten-year ... tested and if negative ... • Infectious causes ... Myelitis #diagnosis #management