13 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... autoantibodies that will cause ... #diagnosis #management ... #treatment
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Positive in 60-80% of cases ... pANCA anti-MPO - Negative ... life-threatening • Treatment ... Evolution: Chronic disease
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... pANCA anti-MPO - Negative ... life-threatening • Treatment ... Usual therapeutic management ... Evolution: Chronic disease
Streptococcal Toxic Shock Syndrome (STSS)
Complication of invasive GAS disease characterized by shock & MOF → occurs
of invasive GAS disease ... GAS in 30% of cases ... kidneys, liver, lung ... #STSS #treatment ... #management #diagnosis
Orthopedic Emergencies
Compartment Syndrome
 • An increase in compartment pressure to the point where tissue perfusion is
• Syndrome caused ... globules in the lung ... including DM • Treatment ... gram positive and negative ... #treatment
Myasthenic Crisis Checklist - Myasthenia Gravis

Evaluation 
 - Chest X-ray and lung ultrasound (exclude other lung
Chest X-ray and lung ... ultrasound (exclude ... other lung disease ... Do not measure negative ... #Management #CriticalCare
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... absence of intrinsic lung ... disease Caused ... on radioactive lung ... #treatment #hepatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Systemic lupus ... rash) • Heart, lung ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... #Diagnosis #Management
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... Goodpasture's cause ... sparing of the lung ... differential #diagnosis #management ... #treatment
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... affected areas and if negative ... and lower jaw Treatment ... osteoarticular and skin disease ... Rheumatology #diagnosis #management