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diagnosis differential rheumatology cardiology sle dermatology erythematosus neurology pharmacology pulmonary chf crisis criticalcare endocarditis heartfailure hematology hepatology infectiousdiseases inflammatory oncology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
central nervous system ... and less common diseases ... diagnosis and treatment ... Inflammatory causes ... • Systemic lupus
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Positive in 60-80% of cases ... pANCA anti-MPO - Negative ... life-threatening • Treatment ... Evolution: Chronic disease
Interstitial Lung Diseases (ILD) Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): • Hypersensitivity pneumonitis, Farmer's lung, Bird
ILD caused by inhalation ... : • Systemic sclerosis ... Polymyositis-dermatomyositis, Lupus ... Churg Strauss syndrome ... differential #pulmonary #causes
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... Treatment: • ... #Lupus #Erythematosus ... #rheumatology #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Demyelinating Syndrome ... Cerebrovascular Disease ... autoantibodies that will cause ... cerebritis #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... rash) • Heart, lung ... lupus erythematosus ... Treatment: • Corticosteroids ... #Diagnosis #Management
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome ... - Treatment Ulcers ... : • Treatment: ... #Syndrome #Treatment ... #management #pharmacology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... months to years) Systemic ... pANCA anti-MPO - Negative ... Usual therapeutic management ... Evolution: Chronic disease
Rhombencephalitis BACTERIAL - Listeria (biphasic illness with bulbar dysfunction occurring later) - Mycobacterium tuberculosis - Pneumococcus - Brucella - Borrelia (Lyme Disease) -
Borrelia (Lyme Disease ... - Systemic Lupus ... - Bickerstaff syndrome ... - small cell lung ... Differential #Diagnosis #Causes
Causes of Acute Pericarditis: Infectious; Viral: Adenovirus Coxsackie virus A and B Echovirus Epstein-Barr virus Hepatitis Human immunodeficiency
Causes of Acute ... Tuberculosis Whipple disease ... Breast Leukemia Lung ... Collagen vascular disease ... Systemic lupus
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