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diagnosis lupus treatment checklist blood comparison differential druginduced product reactions syndrome algorithm anesthesia anesthesiology bundle cardiology challenges crisis dermatology dil
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Summary • Epidemiology ... • Immunologic Workup ... Positive in 60-80% of cases ... pANCA anti-MPO - Negative ... #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... • Immunologic Workup ... pANCA anti-MPO - Negative ... comparison #table #rheumatology ... #diagnosis #management
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... [HCQI reflects long-term ... #Measurement #SLE ... #rheumatology # ... levels #lupus #management
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
biliary, renal, lung ... • Some false negative ... Disease #diagnosis #management ... #phenotypes #workup ... #treatment #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Autoimmune diseases: SLE ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
an underlying cause ... Better call hematology ... some time, let’s see ... , this list is long ... #hematology
Myasthenic Crisis Checklist - Myasthenia Gravis Evaluation - Chest X-ray and lung ultrasound (exclude other lung
ultrasound (exclude ... - Infectious workup ... Do not measure negative ... MyastheniaGravis #Checklist #Management ... #CriticalCare
ECMO Troubleshooting - OnePager Summary ECMO Emergency Protocol - Team should train/practice & have necessary supplies at
Troubleshooting - OnePager Summary ... circuit and can cause ... lung or membrane ... #differential #management ... #criticalcare
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... Rule out other causes ... affected areas and if negative ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management
Intraoperative Laryngospasm and Stridor - Guidelines for Crises in Anaesthesia ❶ Call for help and inform theatre
over-vigorous attempts at lung ... Consider other causes ... has developed negative-pressure ... Checklist #Diagnosis #Management ... #Workup
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