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rheumatology lupus differential erythematosus systemic management signs vasculitis ana anticholinergics antinuclear associations autoantibodies behcet chronic classification cll cold connectivetissuediseases ctild
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... pANCA anti-MPO - Negative ... #comparison #table ... #rheumatology # ... diagnosis #management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
meningitis), MCC CNS symptoms ... Oral aphthae : SLE ... • Arthritis: SLE ... #signs #symptoms ... #rheumatology #
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
PSS: Sjogren syndrome ... rheumatoid arthritis SLE ... LungDisease #CTILD #Diagnosis ... #Differential #Comparison ... #Table #Pulmonary
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Systemic Lupus (SLE ... Cranial nerve lesions ... Demyelinating syndromes ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins. There are 5
toxidrome is a syndrome ... (set of symptoms ... antihistamines #Diagnosis ... Toxicology #Toxidromes #Comparison ... #Table #Anticholinergics
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
overlap syndromes ... Negative association ... erythematosus #diagnosis ... #rheumatology # ... table #ANA
Differentiating NBTE from Infective Endocarditis No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
pathognomonic signs/symptoms ... is required for diagnosis ... conditions: Autoimmune (SLE ... #Endocarditis #comparison ... #table
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
and duration of symptoms ... patients Skin lesions ... angioedema Other symptoms ... #rheumatology # ... comparison #table
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
papulosquamous lesions ... Differential Diagnosis ... Malignancy (e.g. hematologic ... Induced Lupus: • Symptoms ... Erythematosus #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... with no early symptoms ... • Richter’s Syndrome ... #workup #oncology ... #hematology
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