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diagnosis rheumatology erythematosus joint monoarthritis monoarticular polyarthritis polyarticular signs vasculitis algorithm ana antibodies antinuclear arthritis arthropathies arthropathy autoantibodies classification clues
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... Photosensitivity, Butterfly rash ... lesions Abdominal pain ... #SLE #systemic ... erythematosus #signs #symptoms
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Lupus - with Systemic ... (SLE), should have ... other symptoms ... like “butterfly rash ... Joint #Disorders #msk
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... 69% - Malar rash ... #Systemic #Lupus ... autoantibodies #signs #symptoms ... #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... NPSLE rare, Malar rash ... constitutional symptoms ... months to years) Systemic ... pANCA anti-MPO - Negative
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... context of other symptoms ... (SLE), Systemic ... (SLE), Systemic ... #diagnosis #differential
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
Inflammatory joint pain ... and fingers, or pain ... everywhere) 2) A rash ... the face (many differential ... #clues #system
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... Arthritis: • Joint pain ... : • Symptoms limited ... #Systemic #Lupus
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... mucositis - Rash ... lupus erythematosus ... Symptoms (Sx) in ... vasculitis, and SLE
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
- Arthritis Differential ... constitutional symptoms ... aureus • Gram-negative ... #Differential # ... Diagnosis #MSK #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Symptoms (SX) in ... , mucositis • Rash ... • Progressive symptoms ... involvement, abdominal pain
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